Go to
JCI Insight
About
Editors
Consulting Editors
For authors
Publication ethics
Publication alerts by email
Advertising
Job board
Contact
100th anniversary
Current issue
Past issues
By specialty
COVID-19
Cardiology
Gastroenterology
Immunology
Metabolism
Nephrology
Neuroscience
Oncology
Pulmonology
Vascular biology
All ...
Videos
Conversations with Giants in Medicine
Author's Takes
Reviews
Reviews
View all reviews ...
Review Series
Vascular Malformations (Apr 2024)
Lung inflammatory injury and tissue repair (Jul 2023)
Immune Environment in Glioblastoma (Feb 2023)
Korsmeyer Award 25th Anniversary Collection (Jan 2023)
Aging (Jul 2022)
Next-Generation Sequencing in Medicine (Jun 2022)
New Therapeutic Targets in Cardiovascular Diseases (Mar 2022)
View all review series ...
Viewpoint
Collections
In-Press Preview
Commentaries
Research Letters
Letters to the Editor
Editorials
Viewpoint
JCI This Month
Top read articles
Clinical Medicine
Author's Take
0 Articles
174 Posts
No articles were found with this tag.
← Previous
1
2
3
4
5
…
17
18
Next →
Efficient maternal to neonatal transfer of antibodies
In this episode, Michal Kovo explains that antenatal BNT162b2 mRNA vaccination induces a robust maternal humoral response that effectively transfers to the fetus, supporting the role of vaccination during pregnancy...
Published July 1, 2021
Author's Take
Immune checkpoint receptors for HBV infection
In this episode, Shie-Liang Hsieh and Tsung-Yu Tsai explain that HBV interacts with SIGLEC-3 and causes impairment of host immunity...
Published June 1, 2021
Author's Take
CCL17-producing cDC2s in end-stage lupus nephritis and parasitic infections
In this episode, Laura Amo and Silvia Bolland explain that the infiltration into kidneys of iDC2s, with potential to prime local adaptive responses, is an essential regulated event...
Published June 1, 2021
Author's Take
Frataxin deficiency and pulmonary hypertension
In this episode, Stephen Chan explains that genetic and acquired frataxin deficiency disrupts genomic integrity to induce endothelial senescence and represents a common mechanism for multiple pulmonary hypertension subtypes...
Published June 1, 2021
Author's Take
Regulation of proteome degradation in arrhythmogenic right ventricular dysplasia/cardiomyopathy
In this episode, Farah Sheikh presents the identification of a desmosomal COP9 signalosome regulatory complex that restricts desmosomal proteome degradation and genetic cardiac desmosomal disease, arrhythmogenic right ventricular cardiomyopathy...
Published June 1, 2021
Author's Take
Thymosin β4 protects against aortic aneurysm
In this episode, Nicola Smart, Sonali Munshaw, and Susann Bruche present their findings that Thymosin β4 is a regulator of LRP1, which protects against aortic aneurysm by regulating PDGFRβ endocytosis and smooth muscle phenotype...
Published May 17, 2021
Author's Take
Impairing melanoma phenotype switching and potentiating antitumor immune responses
In this episode, Sonia del Rincón and Fan Huang explain that inhibiting the MNK1/2-eIF4E axis dampens melanoma plasticity and enhances response to anti-PD-1 immunotherapy...
Published April 22, 2021
Author's Take
Lipid-induced cell adhesion promotes nonalcoholic steatohepatitis pathogenesis
In this episode, Samar Ibrahim explains that lipotoxic stress enhances the expression of LSEC-VCAM-1, in part, through MLK3 signaling...
Published March 15, 2021
Author's Take
Inflammation of the heart after reperfused myocardial infarction
In this issue, Edward Thorp explains that AXL uniquely promotes a switch to glycolytic metabolism and inflammatory cytokine production by macrophages to worsen ventricular remodeling and lead to heart failure after myocardial infarction...
Published March 15, 2021
Author's Take
N-cadherin upregulation in glioblastoma
In this episode, Erwin Van Meir and Satoru Osuka eplain that glioma stem cells adapt to the toxicity of repeated irradiation by upregulating N-cadherin, and this resistance pathway can be antagonized by blocking the IGF1 receptor...
Published March 15, 2021
Author's Take
← Previous
1
2
3
4
5
…
17
18
Next →
Advertisement