HIV-1 drug resistance profiles in children and adults with viral load of< 50 copies/ml receiving combination therapy
M Hermankova, SC Ray, C Ruff, M Powell-Davis… - Jama, 2001 - jamanetwork.com
ContextThe continued release of human immunodeficiency virus type 1 (HIV-1) into plasma
at very low levels during highly active antiretroviral therapy (HAART) can be detected using
specialized techniques, but the nature and significance of this low-level viremia, especially
as related to acquisition of drug resistance mutations, are unclear. ObjectiveTo determine
genetic resistance profiles of low-level plasma HIV-1 in patients with prolonged viral
suppression (< 50 copies/mL of plasma HIV-1 RNA) while receiving HAART. Design and …
at very low levels during highly active antiretroviral therapy (HAART) can be detected using
specialized techniques, but the nature and significance of this low-level viremia, especially
as related to acquisition of drug resistance mutations, are unclear. ObjectiveTo determine
genetic resistance profiles of low-level plasma HIV-1 in patients with prolonged viral
suppression (< 50 copies/mL of plasma HIV-1 RNA) while receiving HAART. Design and …