SLDAssay: a software package and web tool for analyzing limiting dilution assays

IM Trumble, AG Allmon, NM Archin, J Rigdon… - Journal of …, 2017 - Elsevier
Serial limiting dilution (SLD) assays are used in many areas of infectious disease related
research. This paper presents SLDAssay, a free and publicly available R software package
and web tool for analyzing data from SLD assays. SLDAssay computes the maximum
likelihood estimate (MLE) for the concentration of target cells, with corresponding exact and
asymptotic confidence intervals. Exact and asymptotic goodness of fit p-values, and a bias-
corrected (BC) MLE are also provided. No other publicly available software currently …