Propranolol vs prednisolone for symptomatic proliferating infantile hemangiomas: a randomized clinical trial
NM Bauman, RJ McCarter, PC Guzzetta… - … –Head & Neck …, 2014 - jamanetwork.com
Importance While propranolol is touted as superior to prednisolone for treating infantile
hemangiomas (IH), a randomized clinical trial (RCT) comparing the outcome and tolerability
of these medications for symptomatic, proliferating IH has not been reported. Objectives To
determine if oral propranolol is more efficacious and better tolerated than prednisolone in
treating symptomatic, proliferating IH and to determine the feasibility of conducting a multi-
institutional, RCT comparing efficacy and tolerability of both medications. Design, Setting …
hemangiomas (IH), a randomized clinical trial (RCT) comparing the outcome and tolerability
of these medications for symptomatic, proliferating IH has not been reported. Objectives To
determine if oral propranolol is more efficacious and better tolerated than prednisolone in
treating symptomatic, proliferating IH and to determine the feasibility of conducting a multi-
institutional, RCT comparing efficacy and tolerability of both medications. Design, Setting …