The use of therapeutic antibodies, delivered by intravenous (IV) instillation, is a rapidly
expanding area of biomedical treatment for a variety of conditions. However, little is known
about how the antibodies are anatomically distributed following infusion and the underlying
mechanism mediating therapeutic antibody distribution to specific anatomical sites remains
to be elucidated. Current efforts utilize low resolution and sensitivity methods such as ELISA
and indirect labeling imaging techniques, which often leads to high background and …