Brain microglia and blood-derived macrophages: molecular profiles and functional roles in multiple sclerosis and animal models of autoimmune demyelinating …
G Raivich, R Banati - Brain Research Reviews, 2004 - Elsevier
Microglia and macrophages, one a brain-resident, the other a mostly hematogenous cell
type, represent two related cell types involved in the brain pathology in multiple sclerosis
and its autoimmune animal model, the experimental allergic encephalomyelitis. Together,
they perform a variety of different functions: they are the primary sensors of brain pathology,
they are rapidly recruited to sites of infection, trauma or autoimmune inflammation in
experimental allergic encephalomyelitis and multiple sclerosis and they are competent …
type, represent two related cell types involved in the brain pathology in multiple sclerosis
and its autoimmune animal model, the experimental allergic encephalomyelitis. Together,
they perform a variety of different functions: they are the primary sensors of brain pathology,
they are rapidly recruited to sites of infection, trauma or autoimmune inflammation in
experimental allergic encephalomyelitis and multiple sclerosis and they are competent …
