The relation between peripheral blood leukocyte counts and respiratory symptoms, atopy, lung function, and airway responsiveness in adults

SA Lewis, ID Pavord, JR Stringer, AJ Knox, ST Weiss… - Chest, 2001 - Elsevier
Study objectives: Eosinophils and neutrophils playmajor roles, respectively, in the
pathogenesis of asthma and COPD, andit is well recognized that levels of these cells in
peripheral bloodare increased in relation to their pulmonary involvement. However,
therelation between peripheral blood cell counts of the other majorleukocyte groups and
these lung diseases or markers of allergy orairflow obstruction is less clear. We have
therefore investigated theassociation between peripheral blood levels of eosinophils …