[HTML][HTML] The role of neutrophils during intestinal inflammation

BM Fournier, CA Parkos - Mucosal immunology, 2012 - Elsevier
Polymorphonuclear leukocytes or neutrophils play a critical role in the maintenance of
intestinal homeostasis. They have elegant defense mechanisms to eliminate microbes that
have translocated across a single layer of mucosal epithelial cells that form a critical barrier
between the gut lumen and the underlying tissue. During the inflammatory response,
neutrophils also contribute to the recruitment of other immune cells and facilitate mucosal
healing by releasing mediators necessary for the resolution of inflammation. Although the …