Age-related change and its sex differences in histoarchitecture of the hypothalamic suprachiasmatic nucleus of F344/N rats

S Tsukahara, S Tanaka, K Ishida, N Hoshi… - Experimental …, 2005 - Elsevier
The present study examined the effects of aging and sex differences on the suprachiasmatic
nucleus (SCN) of F344/N rats. In juveniles (1.6–1.9 months of age), adults (11.7–16.3
months of age), and old (29.2–34 months of age) rats, the volume, size of neuronal nucleus
and neuronal cell number of the SCN were determined with cresyl fast violet-stained
sections. In addition, immunohistochemical analysis was performed for glial fibrillary acidic
protein (GFAP). There was no significant effect of aging and sex differences on the SCN …