[HTML][HTML] The role of microRNAs in skeletal muscle health and disease
Frontiers in bioscience (Landmark edition), 2015•ncbi.nlm.nih.gov
Over the last decade non-coding RNAs have emerged as importance regulators of gene
expression. In particular, microRNAs are a class of small RNAs of~ 22 nucleotides that
repress gene expression through a post-transcriptional mechanism. MicroRNAs have been
shown to be involved in a broader range of biological processes, both physiological and
pathological, including myogenesis, adaptation to exercise and various myopathies. The
purpose of this review is to provide a comprehensive summary of what is currently known …
expression. In particular, microRNAs are a class of small RNAs of~ 22 nucleotides that
repress gene expression through a post-transcriptional mechanism. MicroRNAs have been
shown to be involved in a broader range of biological processes, both physiological and
pathological, including myogenesis, adaptation to exercise and various myopathies. The
purpose of this review is to provide a comprehensive summary of what is currently known …
Abstract
Over the last decade non-coding RNAs have emerged as importance regulators of gene expression. In particular, microRNAs are a class of small RNAs of~ 22 nucleotides that repress gene expression through a post-transcriptional mechanism. MicroRNAs have been shown to be involved in a broader range of biological processes, both physiological and pathological, including myogenesis, adaptation to exercise and various myopathies. The purpose of this review is to provide a comprehensive summary of what is currently known about the role of microRNAs in skeletal muscle health and disease.
ncbi.nlm.nih.gov