[HTML][HTML] Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer
J Nilsson, J Skog, A Nordstrand, V Baranov… - British journal of …, 2009 - nature.com
J Nilsson, J Skog, A Nordstrand, V Baranov, L Mincheva-Nilsson, XO Breakefield…
British journal of cancer, 2009•nature.comHerein, we describe a novel approach in the search for prostate cancer biomarkers, which
relies on the transcriptome within tumour exosomes. As a proof-of-concept, we show the
presence of two known prostate cancer biomarkers, PCA-3 and TMPRSS2: ERG the in
exosomes isolated from urine of patients, showing the potential for diagnosis and monitoring
cancer patients status.
relies on the transcriptome within tumour exosomes. As a proof-of-concept, we show the
presence of two known prostate cancer biomarkers, PCA-3 and TMPRSS2: ERG the in
exosomes isolated from urine of patients, showing the potential for diagnosis and monitoring
cancer patients status.
Abstract
Herein, we describe a novel approach in the search for prostate cancer biomarkers, which relies on the transcriptome within tumour exosomes. As a proof-of-concept, we show the presence of two known prostate cancer biomarkers, PCA-3 and TMPRSS2: ERG the in exosomes isolated from urine of patients, showing the potential for diagnosis and monitoring cancer patients status.
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