Antiprostasome antibodies: possible serum markers for prostate cancer metastasizing liability

A Larsson, G Ronquist, C Wülfing, E Eltze… - … Oncology: Seminars and …, 2006 - Elsevier
Prostasomes are secretory granules synthesized, stored, and secreted by normal and
neoplastic human prostate epithelial cells. In prostate cancer, they are anticipated to be
released into the blood circulation where they may be immunogenic. The aim of our study
was to examine whether prostasome antibody presence in serum bears any prognostic
significance for men with prostate cancer. We developed a sensitive and specific
immunoassay (enzyme-linked immunosorbent assay) to establish the presence of …