The familial nature of multiple sclerosis: age‐corrected empiric recurrence risks for children and siblings of patients

AD Sadovnick, PA Baird - Neurology, 1988 - AAN Enterprises
AD Sadovnick, PA Baird
Neurology, 1988AAN Enterprises
Increasingly, MS patients ask neurologists about the risk that their close relatives will also
develop MS. We calculated age-adjusted empiric recurrence risks from data on 815 index
cases and over 3,000 of their siblings and children. In general, the risk for these relatives to
develop MS is 3 to 5%, which is 30 to 50 times the 0.1% rate for the general population.
Increasingly, MS patients ask neurologists about the risk that their close relatives will also develop MS. We calculated age-adjusted empiric recurrence risks from data on 815 index cases and over 3,000 of their siblings and children. In general, the risk for these relatives to develop MS is 3 to 5%, which is 30 to 50 times the 0.1% rate for the general population.
American Academy of Neurology