Role of endogenous and induced regulatory T cells during infections
E Wohlfert, Y Belkaid - Journal of clinical immunology, 2008 - Springer
Journal of clinical immunology, 2008•Springer
Background Various populations of regulatory cells, including Foxp3+ T Reg, have been
shown to play a central role in the maintenance of peripheral homeostasis and
establishment of controlled immune responses. Objective In this review, we discuss current
hypotheses and points of polemic associated with the origin, mode of action, and antigen
specificity of both endogenous and induced regulatory T cells during infections.
shown to play a central role in the maintenance of peripheral homeostasis and
establishment of controlled immune responses. Objective In this review, we discuss current
hypotheses and points of polemic associated with the origin, mode of action, and antigen
specificity of both endogenous and induced regulatory T cells during infections.
Background
Various populations of regulatory cells, including Foxp3+ TReg, have been shown to play a central role in the maintenance of peripheral homeostasis and establishment of controlled immune responses.
Objective
In this review, we discuss current hypotheses and points of polemic associated with the origin, mode of action, and antigen specificity of both endogenous and induced regulatory T cells during infections.
Springer