Mammalian glucokinase

RL Printz, MA Magnuson… - Annual review of nutrition, 1993 - annualreviews.org
Annual review of nutrition, 1993annualreviews.org
Glucose transport and phosphorylation are the initial events in glucose utilization by all
tissues and cell types. The necessary first step in glucose utilization, the movement of the
molecule across the plasma membrane, is accomplished by a family of glucose transporters,
designated GLUT 1-5, that operate by facilitated diffusion to move glucose down a high to
low concentration gradient (10, 78, 85). Glucose uptake occurs when the
Glucose transport and phosphorylation are the initial events in glucose utilization by all tissues and cell types. The necessary first step in glucose utilization, the movement of the molecule across the plasma membrane, is accomplished by a family of glucose transporters, designated GLUT 1-5, that operate by facilitated diffusion to move glucose down a high to low concentration gradient (10, 78, 85). Glucose uptake occurs when the
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