Background/Aims: Angiogenesis is essential in liver regeneration. However, only little is
known about sinusoidal endothelial cell proliferation and the role of different angiogenic
growth factors and their receptors during regeneration. Methods: Seventy percent
hepatectomy was carried out on male rats. Serial changes in endothelial cell proliferation
were evaluated by immunohistochemistry. The mRNA expressions of angiogenic growth
factors (vascular endothelial growth factor (VEGF) and angiopoietins 1 and 2) and their …