[HTML][HTML] Endothelial-monocyte–activating polypeptide II induces migration of endothelial progenitor cells via the chemokine receptor CXCR3

Y Hou, PA Plett, DA Ingram, G Rajashekhar… - Experimental …, 2006 - Elsevier
OBJECTIVE: Recruitment of endothelial progenitor cells to the sites of ischemia has recently
been suggested as a mechanism of tissue repair. Here we address the hypothesis that the
hypoxia-inducible full-length endothelial-monocyte-activating polypeptide II (EMAP II)
provides a mechanism to recruit late outgrowth highly proliferating endothelial progenitor
cells (EPCs). MATERIALS AND METHODS: We tested in a transwell migration assay EMAP
II for its ability to induce migration of EPCs. Furthermore, we measured changes in cellular …