Bloom's syndrome

J German - Dermatologic clinics, 1995 - derm.theclinics.com
Bloom's syndrome is a rare autosomal recessively transmitted disorder, the main clinical
feature of which is small body size. A sun-sensitive, erythematous facial skin lesion, an
excess of well-demarcated hyper-and hypopigmented skin lesions located anywhere on the
body, and increased numbers of bacterial infections due to immunodeficiency are
accompanying features of diagnostic value. In Bloom's syndrome, the complications are
formidable: cancer, chronic lung disease, and diabetes. Cancers of the types and sites seen …