Regulation of signal transduction by endocytosis
BP Ceresa, SL Schmid - Current opinion in cell biology, 2000 - Elsevier
BP Ceresa, SL Schmid
Current opinion in cell biology, 2000•ElsevierEndocytosis of ligand-activated receptors has generally been considered a mechanism to
attenuate signaling. There is now a growing body of evidence suggesting that this process is
much more sophisticated and that endocytic membrane trafficking regulates both the
intensity of signaling and the co-localization of activated receptors with downstream
signaling molecules.
attenuate signaling. There is now a growing body of evidence suggesting that this process is
much more sophisticated and that endocytic membrane trafficking regulates both the
intensity of signaling and the co-localization of activated receptors with downstream
signaling molecules.
Endocytosis of ligand-activated receptors has generally been considered a mechanism to attenuate signaling. There is now a growing body of evidence suggesting that this process is much more sophisticated and that endocytic membrane trafficking regulates both the intensity of signaling and the co-localization of activated receptors with downstream signaling molecules.
Elsevier
