Immunohistologic and electron microscopic abnormalities of desmin and dystrophin in familial cardiomyopathy and myopathy.
HH Goebel, T Voit, I Warlo, K Jacobs… - Revue …, 1994 - europepmc.org
HH Goebel, T Voit, I Warlo, K Jacobs, U Johannsen, CR Müller
Revue neurologique, 1994•europepmc.orgA 52-year-old man had a cardiomyopathy for 22 years as had his brother. Both required
pacemakers. For the past 12 years, he also suffered from increasing muscle weakness. His
muscle fibres contained granulo-filamentous material as previously seen in muscle fibres of
a French family with myopathy and cardiomyopathy. It was rich in desmin, alpha-B crystallin,
and dystrophin, the connotation, pathogenesis, and common denominator of which,
however, remain unexplained.
pacemakers. For the past 12 years, he also suffered from increasing muscle weakness. His
muscle fibres contained granulo-filamentous material as previously seen in muscle fibres of
a French family with myopathy and cardiomyopathy. It was rich in desmin, alpha-B crystallin,
and dystrophin, the connotation, pathogenesis, and common denominator of which,
however, remain unexplained.
A 52-year-old man had a cardiomyopathy for 22 years as had his brother. Both required pacemakers. For the past 12 years, he also suffered from increasing muscle weakness. His muscle fibres contained granulo-filamentous material as previously seen in muscle fibres of a French family with myopathy and cardiomyopathy. It was rich in desmin, alpha-B crystallin, and dystrophin, the connotation, pathogenesis, and common denominator of which, however, remain unexplained.
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