Frequency of beryllium-specific, TH1-type cytokine-expressing CD4+ T cells in patients with beryllium-induced disease
GB Pott, BE Palmer, AK Sullivan, L Silviera… - Journal of allergy and …, 2005 - Elsevier
BACKGROUND: Beryllium sensitization is caused by exposure to beryllium in the
workplace. A subset of beryllium-sensitized (BeS) subjects progress to chronic beryllium
disease (CBD), a disorder characterized by a CD4+ T-cell alveolitis and granulomatous
inflammation. Whether biomarkers are present in blood that would allow separation of CBD
from beryllium sensitization without invasive pulmonary procedures is unknown.
OBJECTIVE: The aim of this study was to determine whether the quantity of beryllium …
workplace. A subset of beryllium-sensitized (BeS) subjects progress to chronic beryllium
disease (CBD), a disorder characterized by a CD4+ T-cell alveolitis and granulomatous
inflammation. Whether biomarkers are present in blood that would allow separation of CBD
from beryllium sensitization without invasive pulmonary procedures is unknown.
OBJECTIVE: The aim of this study was to determine whether the quantity of beryllium …
