ContextPreimplantation genetic diagnosis (PGD) has become an option for couples for
whom termination of an affected pregnancy identified by traditional prenatal diagnosis is
unacceptable and is applicable to indications beyond those of prenatal diagnosis, such as
HLA matching to affected siblings to provide stem cell transplantation. ObjectiveTo describe
preimplantation HLA typing, not involving identification of a causative gene, for couples who
had children with bone marrow disorders at need for HLA-matched stem cell transplantation …