The adhesin structures involved in the adherence of group B streptococci to human vaginal cells
TN Bulgakova, KB Grabovskaya, M Rýc… - Folia microbiologica, 1986 - Springer
TN Bulgakova, KB Grabovskaya, M Rýc, J Jelínkovác
Folia microbiologica, 1986•SpringerThe adherence of group B streptococci (GBS) of serotypes Ia, II and III to human vaginal
cells was studied in vitro. The adherence was not dependent on the viability of bacteria;
killing of GBS by UV irradiation or glutaraldehyde treatment did not inhibit the adherence.
Killing of GBS by heating to 56° C for 1 h led to a pronounced decrease of adherence,
demonstrating the thermosensitivity of the GBS structures involved. The protein nature of
these structures was proved by a significant reduction of adherence after pretreatment of …
cells was studied in vitro. The adherence was not dependent on the viability of bacteria;
killing of GBS by UV irradiation or glutaraldehyde treatment did not inhibit the adherence.
Killing of GBS by heating to 56° C for 1 h led to a pronounced decrease of adherence,
demonstrating the thermosensitivity of the GBS structures involved. The protein nature of
these structures was proved by a significant reduction of adherence after pretreatment of …
Abstract
The adherence of group B streptococci (GBS) of serotypes Ia, II and III to human vaginal cells was studiedin vitro. The adherence was not dependent on the viability of bacteria; killing of GBS by UV irradiation or glutaraldehyde treatment did not inhibit the adherence. Killing of GBS by heating to 56 °C for 1 h led to a pronounced decrease of adherence, demonstrating the thermosensitivity of the GBS structures involved. The protein nature of these structures was proved by a significant reduction of adherence after pretreatment of GBS with trypsin or pepsin. Pretreatment of GBS with sialidase had no influence on the adherence. Such a pretreatment of vaginal cells caused an increase of adherence showing that the receptors on epithelial cells may be partly masked by sialic acid.
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