Addressing the insulin resistance syndrome: a role for the thiazolidinediones
P Zimmet - Trends in Cardiovascular Medicine, 2002 - Elsevier
The global epidemic of type 2 diabetes and cardiovascular disease (CVD) is mirrored by
increasing prevalence of the Insulin Resistance Syndrome (IRS) or Metabolic Syndrome.
Accumulating data indicate that insulin resistance is the common denominator underlying
this cluster of related CVD risk factors. Therapeutic interventions that address insulin
resistance and other components of the IRS may be of benefit in reducing the significant
health and socioeconomic burden presented by diabetes and CVD. Evidence is discussed …
increasing prevalence of the Insulin Resistance Syndrome (IRS) or Metabolic Syndrome.
Accumulating data indicate that insulin resistance is the common denominator underlying
this cluster of related CVD risk factors. Therapeutic interventions that address insulin
resistance and other components of the IRS may be of benefit in reducing the significant
health and socioeconomic burden presented by diabetes and CVD. Evidence is discussed …