[HTML][HTML] Inhibition of carnitine palmitoyltransferase in the rat small intestine reduces export of triacylglycerol into the lymph
LT Washington, GA Cook, CM Mansbach II - Journal of lipid research, 2003 - ASBMB
Following digestion of dietary triacylglycerol (TAG), intestinal epithelial cells absorb fatty
acids and monoacylglycerols that are resynthesized into TAG by enzymes located on the
endoplasmic reticulum (ER). A study in rat liver (Abo-Hashema, KA, MH Cake, GW Power,
and DJ Clarke. 1999. Evidence for TAG synthesis in the lumen of microsomes via a lipolysis-
esterification pathway involving carnitine acyltransferases. J. Biol. Chem. 274: 35577–
35582) showed that there is a carnitine-dependent ER lumenal synthesis of TAG. We …
acids and monoacylglycerols that are resynthesized into TAG by enzymes located on the
endoplasmic reticulum (ER). A study in rat liver (Abo-Hashema, KA, MH Cake, GW Power,
and DJ Clarke. 1999. Evidence for TAG synthesis in the lumen of microsomes via a lipolysis-
esterification pathway involving carnitine acyltransferases. J. Biol. Chem. 274: 35577–
35582) showed that there is a carnitine-dependent ER lumenal synthesis of TAG. We …
