[HTML][HTML] A carboxyl-terminal PDZ-interacting domain of scavenger receptor B, type I is essential for cell surface expression in liver
DL Silver - Journal of Biological Chemistry, 2002 - ASBMB
Scavenger receptor B, type I (SR-BI) was recently shown to interact with a PDZ domain-
containing protein, PDZK1 (CLAMP/Diphor-1/CAP70/NaPi-Cap1), but the importance of this
interaction in vivo in terms of SR-BI function has not been determined. In an effort to
elucidate the role of this interactionin vivo, the PDZK1-interacting domain of SR-BI was
identified and mutated and expressed liver-specifically in mice. The PDZKI-interacting
domain on SR-BI was identified as the last three carboxyl-terminal amino acids, Arg-Lys …
containing protein, PDZK1 (CLAMP/Diphor-1/CAP70/NaPi-Cap1), but the importance of this
interaction in vivo in terms of SR-BI function has not been determined. In an effort to
elucidate the role of this interactionin vivo, the PDZK1-interacting domain of SR-BI was
identified and mutated and expressed liver-specifically in mice. The PDZKI-interacting
domain on SR-BI was identified as the last three carboxyl-terminal amino acids, Arg-Lys …
