Alcohol metabolism is one of the biological determinants that can significantly influence
drinking behavior and the development of alcoholism and alcohol-induced organ damage.
Most ethanol elimination occurs by oxidation to acetaldehyde and acetate, catalyzed
principally by alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Other
ethanol oxidation pathways, including catalase and microsomal ethanol-oxidizing system
(MEOS/CYP2E1), as well as the nonoxidative pathway (FAEES), which forms fatty acid ethyl …