Plasmodium falciparum antimalarial drug susceptibility on the north-western border of Thailand during five years of extensive use of artesunate-mefloquine
A Brockman, RN Price, M Van Vugt… - Transactions of the …, 2000 - Elsevier
Following a marked decline in the efficacy in vivo of mefloquine between 1990 and 1994, a
combination of artesunate (4 mg/kg/d for 3 d) and mefloquine (25 mg/kg) has been used as
first line treatment of uncomplicated falciparum malaria in camps for displaced persons
located along the north-western border of Thailand. Antimalarial drug susceptibility of fresh
isolates of Plasmodium falciparum from this population was evaluated using a radioisotope
microdilution assay between 1995 and 1999. In total, 268 isolates were collected, of which …
combination of artesunate (4 mg/kg/d for 3 d) and mefloquine (25 mg/kg) has been used as
first line treatment of uncomplicated falciparum malaria in camps for displaced persons
located along the north-western border of Thailand. Antimalarial drug susceptibility of fresh
isolates of Plasmodium falciparum from this population was evaluated using a radioisotope
microdilution assay between 1995 and 1999. In total, 268 isolates were collected, of which …