[HTML][HTML] Nonreplication in genetic association studies of obesity and diabetes research

DT Redden, DB Allison - The Journal of nutrition, 2003 - Elsevier
The objective of this article is to provide an overview of the existing literature concerning the
identification of genetic markers associated with obesity and diabetes. Specifically, this
article will review recent association studies of diabetes and obesity with an emphasis on
the need for the replication of findings. Unfortunately, a substantial number of the published
associations between genetic markers and phenotypes, including diabetes and obesity,
have not been replicated. Literature that addresses the potential reasons for the …