Norepinephrine and serotonin alterations following chronic stressor exposure: mouse strain differences
N Shanks, J Griffiths, H Anisman - Pharmacology Biochemistry and …, 1994 - Elsevier
Exposure to acute uncontrolable foot shock influenced the levels and utilization of
norepinephrine (NE) and serotonin (5-HT) in several brain regions. These effects varied
between the BALB/cByJ and C57BL/6J mouse strains, with the former displaying more
pronounced amine variations. Following repeated exposure to foot shock over 15 days, the
decline of NE associated with an acute stressor was abrogated. In the hypothalamus, this
was accompanied by high MHPG accumulation, suggesting that the increased NE stemmed …
norepinephrine (NE) and serotonin (5-HT) in several brain regions. These effects varied
between the BALB/cByJ and C57BL/6J mouse strains, with the former displaying more
pronounced amine variations. Following repeated exposure to foot shock over 15 days, the
decline of NE associated with an acute stressor was abrogated. In the hypothalamus, this
was accompanied by high MHPG accumulation, suggesting that the increased NE stemmed …
