[HTML][HTML] Molecular interactions and functional interference between vitronectin and transforming growth factor-β
M Schoppet, T Chavakis, N Al-Fakhri, SM Kanse… - Laboratory …, 2002 - Elsevier
Different extracellular matrix proteins have been described as binding proteins for growth
factors, influencing their storage or presentation towards cellular receptors. The
multifunctional adhesive glycoprotein vitronectin (VN), which is found in the circulation and
widely distributed throughout different tissues, has been implicated in the regulation of
vascular cell functions, and these activities could be related to interactions with various
growth factors. In vitro, soluble VN interfered with transforming growth factor-β (TGF-β) …
factors, influencing their storage or presentation towards cellular receptors. The
multifunctional adhesive glycoprotein vitronectin (VN), which is found in the circulation and
widely distributed throughout different tissues, has been implicated in the regulation of
vascular cell functions, and these activities could be related to interactions with various
growth factors. In vitro, soluble VN interfered with transforming growth factor-β (TGF-β) …