Effect of hypoxia on the hematopoietic and immune modulator preprotachykinin-I
DP Quinlan Jr, P Rameshwar, J Qian… - Archives of …, 1998 - jamanetwork.com
Objectives To determine the effect of hypoxia on bone marrow mononuclear cells (BMMCs)
and their ability to proliferate into granulocyte-macrophage colony-forming units (CFU-GMs)
and erythroid burst-forming units (BFU-Es) and to determine the role of the neuroimmune
and hematopoietic mediator, substance P. Design Controlled in vitro study. Setting
University research laboratory. Materials Bone marrow aspirates were obtained from the
posterior iliac crests of healthy volunteers after obtaining informed consent. Interventions …
and their ability to proliferate into granulocyte-macrophage colony-forming units (CFU-GMs)
and erythroid burst-forming units (BFU-Es) and to determine the role of the neuroimmune
and hematopoietic mediator, substance P. Design Controlled in vitro study. Setting
University research laboratory. Materials Bone marrow aspirates were obtained from the
posterior iliac crests of healthy volunteers after obtaining informed consent. Interventions …
