Electrical properties and active solute transport in rat small intestine: II. Conductive properties of transepithelial routes
Y Okada, A Irimajiri, A Inouye - The Journal of Membrane Biology, 1977 - Springer
Y Okada, A Irimajiri, A Inouye
The Journal of Membrane Biology, 1977•SpringerThe transepithelial resistance, the cell membrane resistance and the ratio of resistances of
the serosal (baso-lateral) to the mucosal (brush border) cell membrane were measured in
rat duodenum, jejunum and ileum by means of microelectrode techniques. These measured
values were not affected in the presence of actively transported solutes in the mucosal
bathing fluid. Contribution of an electrical conductance through the extracellular shunt
pathway to the total transepithelial conductance was quantitatively estimated using an …
the serosal (baso-lateral) to the mucosal (brush border) cell membrane were measured in
rat duodenum, jejunum and ileum by means of microelectrode techniques. These measured
values were not affected in the presence of actively transported solutes in the mucosal
bathing fluid. Contribution of an electrical conductance through the extracellular shunt
pathway to the total transepithelial conductance was quantitatively estimated using an …
Summary
The transepithelial resistance, the cell membrane resistance and the ratio of resistances of the serosal (baso-lateral) to the mucosal (brush border) cell membrane were measured in rat duodenum, jejunum and ileum by means of microelectrode techniques. These measured values were not affected in the presence of actively transported solutes in the mucosal bathing fluid.
Contribution of an electrical conductance through the extracellular shunt pathway to the total transepithelial conductance was quantitatively estimated using an electrically equivalent circuit analysis. These values estimated in respective tissues of small intestine were approx. 95% of the total transepithelial conductance, remaining unaffected by an active solute transport.
From these data, the changes in emf's of the mucosal and serosal membrane induced byd-glucose or glycine were separately evaluated.
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