Striatal size and relative glucose metabolic rate in schizotypal personality disorder and schizophrenia
L Shihabuddin, MS Buchsbaum… - Archives of General …, 2001 - jamanetwork.com
Background Schizotypal personality disorder (SPD) shares social deficits and cognitive
impairment with schizophrenia, but is not typically characterized by frank psychosis.
Because striatal size and functional activity have both been shown to be associated with
psychotic symptoms, we carried out the first study of SPD to assess the caudate and
putamen for comparison with findings in schizophrenia. Methods Patients with SPD (n= 16),
schizophrenic patients (n= 42), and age-and sex-matched normal control subjects (n= 47) …
impairment with schizophrenia, but is not typically characterized by frank psychosis.
Because striatal size and functional activity have both been shown to be associated with
psychotic symptoms, we carried out the first study of SPD to assess the caudate and
putamen for comparison with findings in schizophrenia. Methods Patients with SPD (n= 16),
schizophrenic patients (n= 42), and age-and sex-matched normal control subjects (n= 47) …
