[PDF][PDF] One hundred years of schizophrenia: a meta-analysis of the outcome literature

JD Hegarty, RJ Baldessarini… - American Journal …, 1994 - madinthenetherlands.org
Objective: This study was undertaken to assess the tuventieth-century literature on outcome
in schizophrenia for historical trends that might be associated with changes in diagnostic
and therapeutic practice and to test the hypothesis that both improved biological treatment
and changes in diagnostic criteria have influenced outcome. Method: Meta-analysis of the
international literature on outcome in schizophrenia or dementia praecox from 1895 to 1992
identified 821 studies; 320 of these, with 51,800 subjects in 368 cohorts, met the inclusion …