[HTML][HTML] Myristic acid-rich fat raises plasma LDL by stimulating LDL production without affecting fractional clearance in gerbils fed a cholesterol-free diet
The imbalance that develops between low-density lipoprotein (LDL) production and
clearance during saturated fat consumption is responsible for expanding the circulating LDL
pool. To assess the imbalance attributable to fatty acids alone, ie, without the interaction of
dietary cholesterol, the most fat-sensitive species available (the gerbil) was challenged with
either a 12: 0+ 14: 0 rich-fat (high coconut, low safflower) or high 18: 2 (high safflower, low
coconut) fat for 4–5 wks. The plasma lipoprotein cholesterol profile, including lipoprotein …
clearance during saturated fat consumption is responsible for expanding the circulating LDL
pool. To assess the imbalance attributable to fatty acids alone, ie, without the interaction of
dietary cholesterol, the most fat-sensitive species available (the gerbil) was challenged with
either a 12: 0+ 14: 0 rich-fat (high coconut, low safflower) or high 18: 2 (high safflower, low
coconut) fat for 4–5 wks. The plasma lipoprotein cholesterol profile, including lipoprotein …
