[PDF][PDF] Developmental expression of the cyclo-oxygenase-1 and cyclo-oxygenase-2 genes in the peri-implantation mouse uterus and their differential regulation by the …
J Chakraborty, SK Das, J Wang… - Journal of molecular …, 1996 - researchgate.net
Cyclo-oxygenase (COX) is a rate-limiting enzyme that converts arachidonic acid to
prostaglandins (PGs) and exists in two isoforms, COX-1 and COX-2. In the rodent, increased
uterine vascular permeability at sites of blastocyst apposition is one of the earliest
prerequisite events in the implantation process. This event is preceded by generalized
uterine edema and luminal closure, and coincides with the initial attachment reaction
between the trophectoderm and luminal epithelium. Vasoactive PGs are implicated in these …
prostaglandins (PGs) and exists in two isoforms, COX-1 and COX-2. In the rodent, increased
uterine vascular permeability at sites of blastocyst apposition is one of the earliest
prerequisite events in the implantation process. This event is preceded by generalized
uterine edema and luminal closure, and coincides with the initial attachment reaction
between the trophectoderm and luminal epithelium. Vasoactive PGs are implicated in these …
