IgE and mucosal immunity: Studies on the role of intraepithelial Ia+ Dendritic Cells and γ/δ T-Lymphocytes in regulation of T-cell activation in the lung.

PG Holt, C McMenamin - Clinical & Experimental Allergy, 1991 - search.ebscohost.com
PG Holt, C McMenamin
Clinical & Experimental Allergy, 1991search.ebscohost.com
Investigates the role of intraepithelial Ia+ Dendritic Cells and γ/δ T-Lymphocytes in
regulation of T-cell activation in the lung. Contact of the T cell population in the alveolar
lining fluids with inhaled antigen; Involvement of selective suppression of antigen-specific
immunoglobulin E antibody production in the natural immune response to initial exposure to
aerosols; Examination of a specialized lineage of predominantly mucosal T-cells which do
not contain conventional & alph;/β chains in their T cell receptors.
Abstract
Investigates the role of intraepithelial Ia+ Dendritic Cells and γ/δ T-Lymphocytes in regulation of T-cell activation in the lung. Contact of the T cell population in the alveolar lining fluids with inhaled antigen; Involvement of selective suppression of antigen-specific immunoglobulin E antibody production in the natural immune response to initial exposure to aerosols; Examination of a specialized lineage of predominantly mucosal T-cells which do not contain conventional & alph;/β chains in their T cell receptors.
search.ebscohost.com